Science

Beckman Coulter Life Sciences Revolutionizes Nanoparticle Analysis, Enabling Characterization Down To 40 nm With Launch of CytoFLEX nano Flow Cytometer


Beckman Coulter Life Sciences, a worldwide chief in laboratory automation and innovation and a subsidiary of Danaher Company (NYSE: DHR), continues to paved the way with first-to-market ideas with the launch of the CytoFLEX nano Stream Cytometer – the primary purpose-built nanoscale movement cytometer for analysis use solely that permits detection to at the very least 40 nm,* enabling 30-50% extra information creation in comparison with present market choices.

With unequalled sensitivity to detect, depend, and characterize nanoparticles utilizing a single analytical instrument, the CytoFLEX nano Stream Cytometer affords simultaneous multiparameter detection powered by six fluorescent detection channels and 5 aspect scatter channels. It supplies world laboratories with a first-of-its form answer that lowers the restrict of detection and will increase decision to characterize decrease abundance targets in heterogeneous extracellular vesicle (EV) populations between 1 μm and 40 nm (polystyrene when triggering on violet aspect scatter).

“The CytoFLEX nano Stream Cytometer shatters the earlier limits of detection capabilities, arming researchers with information they beforehand would have by no means been in a position to entry,” mentioned Product Supervisor Matthew Goff. “This will open new doorways for researchers and allow breakthrough discoveries in our battle towards a myriad of illnesses. Extracellular vesicles will be discovered in all places, and now researchers lastly have a instrument to see what has at all times been proper in entrance of them. We listened to the wants of our prospects to create an analytical crossroads by growing sensitivity via enhanced fluidics, optics, and electronics.”

CytoFLEX nano Flow Cytometer

CytoFLEX nano Stream Cytometer

?Beckman Coulter Life Sciences

Nanoparticles are launched in a hydrodynamic targeted stream to the optical system composed of lasers and detectors. Emitted alerts are collected, digitized, and displayed by the electronics and instrument management software program, CytExpert. A number of automated on-board cleansing choices are supplied to regulate sample-to-sample carryover and preserve a clear pattern line.

“We have to go smaller to broaden the realms of analysis, and there are only a few devices constructed for small particle detection alone,” mentioned Alfonso Blanco, Director of the Stream Cytometry Core Applied sciences within the College Faculty Dublin. “The CytoFLEX nano Stream Cytometer affords a gold mine of analysis discoveries, together with the flexibility to develop advanced biomarkers from blood or urine fairly than extra invasive tissue means, which implies much less ache for sufferers, together with richer outcomes.”

The ergonomic design reduces noise, identifies backgrounds, and reduces carryover points. Constant instrument efficiency from intensive automated QC processes ensures constant and reproducible outcomes each time.

The platform additionally consists of the CytoFLEX, CytoFLEX S, and the CytoFLEX LX movement cytometers, together with the CytoFLEX SRT cell sorter for analysis, and the DxFLEX movement cytometer for diagnostic use. Study extra in regards to the CytoFLEX nano instrument by clicking here.



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